
This challenge stems from the need to analyse noninvasive, objective, and scalable biomarkers, such as speech signals, for early diagnosis and longitudinal monitoring of patients suffering from neurodegenerative diseases. This is because diseases such as Amyotrophic Lateral Sclerosis (ALS), present complex diagnostic challenges due to heterogeneous symptom profiles and overlapping clinical features.

Current diagnostic tools are largely based on subjective clinical scales and often fail to detect early changes, resulting in delayed intervention and suboptimal care for patients. This underscores the urgent need to use noninvasive biomarkers.

With this challenge, we would like to redefine neurodegenerative disease assessment by positioning speech as a central, AI-powered biomarker for diagnosis and monitoring. We invite you to participate in the SAND challenge with your contribution. The five highest-ranked teams will be invited to showcase their work at IEEE ICASSP 2026. Accepted contributions will be published in the official IEEE ICASSP proceedings (IEEE-indexed). The challenge-dedicated session will highlight presentations from the top-performing participants and conclude with a panel discussion. Don’t miss this engaging event!
| Rank | Team Name | F1 Score |
|---|---|---|
| 1° | TUKE 🥇 | 0.6079 |
| 2° | UTL 🥈 | 0.6005 |
| 3° | PRIME 🥉 | 0.5945 |
| 4° | RGTRGT | 0.5849 |
| 5° | CCNYNEURO | 0.5813 |
| 6° | OHTSUKI | 0.5796 |
| 7° | UTAUSTIN | 0.5768 |
| 8° | SARWANALI | 0.5613 |
| 9° | PASSIONAI | 0.5558 |
| 10° | AURA | 0.5437 |
| 11° | TKB | 0.5430 |
| 12° | SLEEPERS | 0.5320 |
| 13° | GTIUNISS | 0.5301 |
| 14° | ISDS | 0.5116 |
| 15° | PATHOLOGICALSPEECH | 0.4820 |
| 16° | MOCHA | 0.4815 |
| 17° | QLN | 0.4804 |
| 18° | CAB | 0.4794 |
| 19° | SSS | 0.4790 |
| 20° | MBS | 0.4751 |
| 21° | UOS | 0.4413 |
| 22° | SMARTVOICE | 0.4231 |
| 23° | SAGI | 0.4175 |
| 24° | SPAGHETTIINHALERS | 0.4159 |
| 25° | CASALAB | 0.4137 |
| 26° | THR | 0.4073 |
| 27° | CLT | 0.3937 |
| 28° | CAU | 0.3937 |
| 29° | SMTIH | 0.3917 |
| 30° | BPGC | 0.3813 |
| 31° | PHOFI | 0.3793 |
| 32° | AICV | 0.3757 |
| 33° | UHL | 0.3725 |
| 34° | DSPLABMARIBOR | 0.3645 |
| 35° | IITPATNA | 0.3634 |
| 36° | TEAMTAG | 0.3629 |
| 37° | CSCU | 0.3623 |
| 38° | GTMN | 0.3596 |
| 39° | JLEE | 0.3398 |
| 40° | GTMUVIGO | 0.3353 |
| 41° | TSY | 0.3078 |
| 42° | STAR | 0.2969 |
| 43° | ECHOPATH | 0.2870 |
| 44° | IMATI | 0.2629 |
| 45° | GISPHEU | 0.2404 |
| 46° | FBK | 0.2025 |
| 47° | WTB | 0.1996 |
| 48° | VAPMR | 0.1888 |
| 49° | TCSSPEECH | 0.1362 |
| 50° | MACEWANVOICES | 0.0992 |
| 51° | ALWAYSMAKEIMPACT | 0.0656 |
| 52° | NETSENSE | 0.0564 |
| Rank | Team Name | F1 Score |
|---|---|---|
| 1° | ISDS 🥇 | 0.5794 |
| 2° | OHTSUKI 🥈 | 0.5637 |
| 3° | JLEE | 0.5612 |
| 4° | CAU | 0.5437 |
| 5° | SPAGHETTIINHALERS | 0.5401 |
| 6° | PATHOLOGICALSPEECH | 0.5278 |
| 7° | ECHOPATH | 0.4994 |
| 8° | CAB | 0.4870 |
| 9° | CLT | 0.4791 |
| 10° | AICV | 0.4552 |
| 11° | CCNYNEURO | 0.4408 |
| 12° | SMARTVOICE | 0.4294 |
| 13° | AURA | 0.4185 |
| 14° | KIE | 0.4097 |
| 15° | HNDX | 0.3879 |
| 16° | PASSIONAI | 0.3815 |
| 17° | SARWANALI | 0.3795 |
| 18° | ARCOLAB | 0.3728 |
| 19° | TKB | 0.3673 |
| 20° | MOCHA | 0.3667 |
| 21° | MBS | 0.3207 |
| 22° | TEAMTAG | 0.3069 |
$$ \text{Avg. F1-Score} = \frac{1}{|C|} \sum_{c \in C} \frac{TP_c}{TP_c + \frac{1}{2}(FP_c + FN_c) } $$
where \(TP_c\) is the number of true positives, \(FP_c\) of False Positives, \(FN_c\) of False Negatives, all reported for class \(c\), while \(|C|\) is \(5\) for task 1, and \(4\) for task 2.
Final rankings will be based on the Avg. F1-score, with higher scores indicating better classification/prediction performance. We chose this metric because it is useful when using unbalanced datasets. In case of a tie, the originality of the proposed approach will serve as an additional evaluation criterion. The final decision will rest with the organizers. Participants may submit results for either one or both tasks. The top five teams will be selected based on performance and the overall distribution of submissions across the tasks (see below for clarification).
ICAR-CNR
ICAR-CNR
ICAR-CNR
University of Campania “Luigi Vanvitelli”
ICAR-CNR
University of Naples “Federico II”
University of Naples “Federico II” and ICAR-CNR
University of Naples “Federico II” and ICAR-CNR
University of Naples “Federico II”
University of Naples “Federico II”
University of Naples “Federico II”
University of Naples “Federico II”
University of Campania “Luigi Vanvitelli”